Indirect Calorimetry — Resting Energy

Free indirect calorimetry calculator: turn measured REE or raw VO₂/VCO₂ into resting energy expenditure, respiratory quotient and substrate oxidation.

Medically reviewed by Dr. Ivan IbáñezNº Col. 17/05487May 29, 2026
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Enter the resting energy expenditure and respiratory quotient already reported by your metabolic cart.

Resting energy expenditure reported by the device.

VCO₂ ÷ VO₂, usually between 0.70 and 1.00.

Used to estimate protein oxidation when urinary nitrogen is not provided.

CalcVita. (2026). Indirect Calorimetry — Resting Energy. CalcVita. Retrieved June 3, 2026, from https://calcvita.com/en/calculators/indirect-calorimetry

Indirect Calorimetry: Measuring Metabolism Beats Guessing

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Indirect Calorimetry: Measuring Metabolism Beats Guessing

Predictive formulas estimate your calorie needs from height, weight and age. Indirect calorimetry measures them directly from the air you breathe — and the difference can be large.

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What indirect calorimetry is

Indirect calorimetry estimates how much energy your body burns by measuring the gases you exchange while breathing: the oxygen you consume (VO₂) and the carbon dioxide you produce (VCO₂). Because fat, carbohydrate and protein each consume oxygen and release CO₂ in fixed ratios, those two gas flows can be converted into a daily calorie figure. This calculator applies the classic Weir (1949) equation to turn VO₂ and VCO₂ into resting energy expenditure (REE).

What VO₂, VCO₂, REE and RQ mean

VO₂ is the volume of oxygen consumed per minute and VCO₂ the volume of carbon dioxide produced per minute. REE (resting energy expenditure) is the calories your body burns at rest over 24 hours — typically 60–75% of total energy expenditure. The respiratory quotient (RQ) is VCO₂ divided by VO₂. RQ reveals which fuel you are oxidising: values near 0.70 indicate mostly fat, around 0.85 a mixed diet, and near 1.00 mostly carbohydrate.

Why measuring beats a predictive equation

Equations such as Mifflin-St Jeor or Harris-Benedict only estimate REE from age, sex, height and weight. They can be off by 10–20% in any individual because they cannot see your actual muscle mass, metabolic adaptation, illness or training status. The ESPEN 2023 practical guideline on clinical nutrition in the intensive care unit recommends measured energy expenditure by indirect calorimetry, when available, as the reference for setting calorie targets — precisely because a real measurement removes that guesswork. This tool shows your measured REE next to the Mifflin-St Jeor prediction so you can see the gap.

How to read substrate oxidation

From VO₂, VCO₂ and (optionally) urinary nitrogen, the Frayn (1983) equations estimate how many grams of fat and carbohydrate you are burning per day, plus the share of energy each fuel provides. A low RQ with high fat oxidation is typical of fasting, low-carb intake or endurance work; a high RQ reflects recent carbohydrate intake or overfeeding. If you do not provide measured urinary nitrogen, protein oxidation is assumed from a percentage of energy and flagged as estimated.

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